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Intrauterine growth restriction causes abnormal embyronic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

ABSTRACT: In our mouse model of intrauterine growth restriction (IUGR), we have discovered that IUGR promotes embyronic Sox2+ neural stem cell depletion as well as premature neurogenesis. Using RNA-seq, we strived to determine the differentially expressed molecular genes/pathways that may be responsible for such cellular differences between appropriately-grown and IUGR mouse offspring.

ORGANISM(S): Mus musculus

PROVIDER: GSE173845 | GEO | 2021/09/15

REPOSITORIES: GEO

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Intrauterine growth restriction causes abnormal embyronic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

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