Effects of aneurysmal low and supra-high wall shear stress on endothelial gene expression

ABSTRACT: Wall shear stress (WSS) is proposed to influence intracranial aneurysm growth and rupture. Physiological WSS in cerebral arteries is estimated around 20-30 dynes/cm2. The WSS typically observed in human IAs is close to 2 dynes/cm2 for wide-neck aneurysms with a slow recirculating flow and >70 dynes/cm2 in aneurysms with impinging “jet flow”. In this study, we investigated the effects of aneurysmal low and supra-high WSS on endothelial cells.

ORGANISM(S): Sus scrofa

PROVIDER: GSE173928 | GEO | 2021/11/04

REPOSITORIES: GEO