Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA sequencing analysis of CD11b+ peritoneal macrophages from WT (C57BL/6), Lum-/- and Bgn-/- mouse.

ABSTRACT: Purpose: To compare transcriptomic changes between untreated and LPS or CpG treated groups in WT, Lum-/- and Bgn-/- peritoneal macrophages.

ORGANISM(S): Mus musculus

PROVIDER: GSE174026 | GEO | 2021/05/07

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

RNA sequencing analysis of CD11b+ peritoneal macrophages from WT (C57BL/6), Lum-/- and Bgn-/- mouse.

Project description:RNA sequencing analysis of CD11b+ peritoneal macrophages from WT (C57BL/6), Lum-/- and Bgn-/- mouse.

| PRJNA728197 | ENA

miRNA profiling in mouse peritoneal macrophages treated without or with LPS

Project description:We have identified a number of miRNAs that are differentially expressed in LPS treated mouse peritoneal macrophages, as compared to untreated cells

2014-02-28 | GSE55414 | GEO

miRNA profiling in mouse peritoneal macrophages treated without or with LPS

Project description:We have identified a number of miRNAs that are differentially expressed in LPS treated mouse peritoneal macrophages, as compared to untreated cells Peritoneal macrophages treated with LPS for 0, 4, 12, 24h. RNA was isolated and miRNA array assays were performed by Exiqon (miRCURY™ LNA Array version 10.0)

2014-02-28 | E-GEOD-55414 | biostudies-arrayexpress

Gene expression of small peritoneal macrophages (SPM)

Project description:Transcriptome of SPM (small peritoneal macrophages) from mice infected with LPS and treated with LCC-12

2023-03-03 | GSE223392 | GEO

Compare RNA profile between LPS+CPN and LPS+CPN+GGOH treated peritoneal macrophages

Project description:To find out genes regulated by geranylgeraniol (GGOH) treatment in peritoneal macrophage, we compared gene expression of cells treated with 200ng ml LPS and 250 micromolar compactin versus 200ng ml LPS, 250 micromolar compactin and 100micromolar GGOH. To find out upregulated or downregulated genes regulated by GGOH treatment in peritoneal macrophage (LPS+CPN treated cell).

2013-11-12 | E-GEOD-48646 | biostudies-arrayexpress

MOUSE peritoneal macrophages treated with C498 or LPS

Project description:Mouse peritoneal macrophages were isolated and treated with vehicle or C498 (15 μM) for 0.5 h, followed by LPS (100 ng/ml) challenge for an additional 4 h.

2023-05-03 | GSE220654 | GEO

Bulk RNA-sequencing in Ldlr-/- peritoneal macrophages treated with LPS

Project description:Here we study the effect of LPS in the transcriptome of thioglycollate-elicited peritoneal macrophages isolated from Ldlr knock out mice

2021-05-21 | GSE168777 | GEO

B cells and peritoneal macrophages RNA-seq

Project description:We found that CD11b-expressing B cells were increased in the BM of LPS-treatmed mice. To examine the differences in gene expression, we isolated CD11b-negative and CD11b-positive B cells were isolated and compared the gene expression profiles with peritoneal macrophages obtained from naive mice by RNA-sequence.

2023-01-24 | GSE222966 | GEO

Expression profiling of Peritoneal Macrophages from lupus-diseased-BWF1 mice and NZW/balbc control mice

Project description:Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies, immune complex deposition, and tissue damage. Several studies have demonstrated the contribution of innate immune cells, including macrophages, in promoting SLE. Macrophages, one of the most abundant cell populations in the peritoneal cavity, are considered multifunctional and phenotypically diverse. Moreover, they can change their phenotype and function in response to environmental signals. However, macrophages' tissue-specific properties in the peritoneal cavity in steady-state and during the progression of SLE remain poorly defined. Using the BWF1 murine model of SLE, we analyzed the phenotype and function of peritoneal macrophages during the disease’s onset. We found a higher frequency of peritoneal macrophages in diseased mice than age-matched controls. Additionally, macrophages from diseased animals expressed lower levels of CD206, MHC-II, and Sirpa. RNAseq analysis identified 286 differentially expressed genes in peritoneal macrophages from diseased-BWF1 mice compared to control mice. Functional experiments demonstrate that peritoneal macrophages from diseased-BWF1 mice secrete higher levels of cytokines when activated with R848 or CpG compared to control cells. Additionally, we observed that peritoneal macrophages from both diseased and control mice could inhibit the activation and proliferation of peritoneal LPS-activated B cells. Advancing awareness of the role and phenotype of peritoneal macrophages in SLE may contribute to a better understanding of these types of diseases and the development of novel therapies.

2021-04-30 | GSE167108 | GEO

Transcriptomic profile of trametinib on LPS-mediated gene expression in murine peritoneal macrophages

Project description:To determine the underlying mechanisms by which trametinib affected LPS-induced inflammatory response in macrophages, we performed microarrays to define the global gene expression in murine peritoneal macrophages treating with trametinib or vehicle followed by LPS stimulation.

2021-07-12 | GSE134486 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data