Examination of HMGA2 binding genes in human HMGA2-exogenous overexpressed gastric cancer cells

ABSTRACT: HMGA2 significantly increased cell proliferation capacity of gastric cancer in a HMGA2-dependent manner both in vivo and in vitro and we found HMGA2 promoted GC through accelerating S-G2/M phase.To elucidate the underlining mechanism by which HMGA2 induced the change of phenotype in GC cells, we performed ChIP-seq analysis of HMGA2-OE MKN-45 cells with anti-HMGA2 antibody.

ORGANISM(S): Homo sapiens

PROVIDER: GSE174442 | GEO | 2021/08/18

REPOSITORIES: GEO