Transcriptional alterations in Type II Rothmund-Thompson Syndrome

ABSTRACT: We generated induced pluripotent stem cell lines (iPSCs) from paired RTS patient/ parental control fibroblasts. These iPSCs were differentiated to mesenchymal stem cells (MSCs), and then to osteoblasts. We next compared the transcriptional profiles of MSCs, pre-osteoblasts, and osteoblasts.

ORGANISM(S): Homo sapiens

PROVIDER: GSE174720 | GEO | 2021/12/01

REPOSITORIES: GEO