Genome wide CRISPR screen for CG-806 resistance in OCI-LY3 cells using Y. Kosuke library

ABSTRACT: OCI-LY3 cells were infected with CRISPR/Cas9 library, selected for puromycin resistance for integration events and exposed to CG-806 or vehicle, DMSO, at 1 microMolar concentrations. Cells were collected at time 0 (post puromycin selection) and day 7. DNA was extracted and sgRNA barcodes were amplified. PCR library was deep sequenced using highthroughput Illumina platform Novaseq 6000.

ORGANISM(S): Homo sapiens

PROVIDER: GSE174766 | GEO | 2023/05/04

REPOSITORIES: GEO