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HDAC5 modulates PD-L1 expression and cancer immunity via p65 deacetylation in pancreatic cancer

ABSTRACT: We performed HDAC5 knockdown in pancreatic cancer cell line (PANC-1). The expression profiling showed NF-κB signaling as a potential HDAC5 targets and the conclusions were futher validated in vivo and in vitro.

ORGANISM(S): Homo sapiens

PROVIDER: GSE175374 | GEO | 2022/03/15

REPOSITORIES: GEO

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HDAC5 modulates PD-L1 expression and cancer immunity via p65 deacetylation in pancreatic cancer

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