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Expression data from Club cells of wt/cTg and Atgl KO/cTg

ABSTRACT: ATGL= the rate-limiting enzyme for intracellular lipolysis. Atgl KO/cTg = Mice lacking Atgl except for cardiac transgenic overexpression of Atgl (Atgl -/- ,Myh6Atgl+/+) to rescue early age death deu to cardiomyopathy. wt/cTg = respective control. The airways of the lung are constantly exposed to inhaled toxic substances, resulting in cellular damage. Within bronchii, club cells make up majority of the cell population in the terminal bronchiolar epithelia. Club cells are known for their ability to metabolize environmental toxins and constantly repairing small impacts in the epithelial layer. Considering the importance of club cells in maintaining bronchiolar epithelial integrity, we porformed gene expression data analysis to decipher the possible dysregulated gene expression thereby corresponding molecular pathways in our mice lacking ATGL.

ORGANISM(S): Mus musculus

PROVIDER: GSE175659 | GEO | 2021/05/28

REPOSITORIES: GEO

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Expression data from Club cells of wt/cTg and Atgl KO/cTg

Project description:Expression data from Club cells of wt/cTg and Atgl KO/cTg

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