A single cell RNA-Seq study of splenic marginal zone lymphomas (SMZL)

ABSTRACT: Purpose: Single cell RNA-Seq was used to characterize in depth splenic samples obtained from splenic marginal zone lymphomas Methods: 3 frozen samples of spleen from SMZL patients were selected and thawed for performing a 10X genomics single cell RNA-Sequencing 3' assay. Results: Tumor cells formed mainly patient specific-B cell clusters, while T-cells from the 3 patients clustered together. Conclusion: Single RNA-Seq unveils the cellular composition of splenic tumors from SMZL patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE175785 | GEO | 2021/10/31

REPOSITORIES: GEO