Transcriptomics

Dataset Information

0

RNA-Seq of isogenic human iPS cell-derived cardiomyocytes with RBM20 mutations created by genome editing (RiboMinus RNA-Seq)


ABSTRACT: RBM20 heterozygous (Het) and homozygous (Homo) R636S and homozygous 8-bp deletion (which causes nonsense-mediated decay) mutations were created by genome editing in an iPS cell line generated from a healthy male patient. Those cells were differentiated into cardiomyocytes by modulating the WNT signaling pathway, and then are subjected to the lactate purification method.

ORGANISM(S): Homo sapiens

PROVIDER: GSE175885 | GEO | 2021/06/01

REPOSITORIES: GEO

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