Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from HCC1954 cells treated with DMSO, Melatonin (mela), Lapatinib (lapa) and their combination(m_l)

ABSTRACT: Drug treatment-induced transcriptional changes in HCC1954 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE175906 | GEO | 2021/11/30

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Expression data from HCC1954 cells treated with DMSO, Melatonin (mela), Lapatinib (lapa) and their combination(m_l)

Project description:Expression data from HCC1954 cells treated with DMSO, Melatonin (mela), Lapatinib (lapa) and their combination(m_l)

| PRJNA734285 | ENA

Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD)

Project description:Drug treatment-induced transcriptional changes in A2780 cells.

2019-06-20 | GSE126998 | GEO

mRNA-seq of HCC1954 siControl and siUSP22

Project description:The analysis of genes affected upon USP22 kcnockdown in HCC1954 cells

2020-08-31 | E-MTAB-8256 | biostudies-arrayexpress

mRNA-seq of HCC1954 siControl and siRNF40

Project description:The analysis of genes affected upon RNF40 knockdown in HCC1954 cells

2020-11-16 | E-MTAB-9234 | biostudies-arrayexpress

Baseline Expression of Inflammatory Cytokines and Receptors in the HCC1954 Human Breast Cancer Cell Line

Project description:Immortalized human breast cancer cell line, HCC1954, was analyzed via RT-qPCR for transcript expression of selected cytokines and cytokine receptors associated with promotion of tumor vasculature and breast cancer metastasis

2016-05-06 | GSE80643 | GEO

Transcriptomic and Epigenetic analysis of cell line derivatives from H2087 and HCC1954 cell lines

Project description:We profiled the transcriptomes of latency-competent cells derived from the human cancer cell lines H2087 (lung adenocarcinoma) and HCC1954 (breast adenocarcinoma) in mitogen-rich and mitogen-low media (MRM and MLM, respectively). In addition, we analyzed the epigenetic landscape of these cell lines under MLM conditions. H2087 and HCC1954 parental and latency-competent cell derivatives (LCCs) were grown for 48hr in mitogen-rich or mitogen-low conditions in vitro, and whole RNA was extracted for RNA-seq profiling. Cell lines were also grown in MLM conditions and DNA extracted for ChIP-Seq experiments.

2016-03-29 | E-GEOD-72956 | biostudies-arrayexpress

Transcriptomic analysis of HCC1954 Parental(Pa), synchronous (S-BM), latent residual (Lat) or metachronous (M-BM) brain metastases cells

Project description:We did the transcriptomic profiling of HCC1954 Parental(Pa), synchronous (S-BM), latent residual (Lat) or metachronous (M-BM) brain metastases cells

2022-07-27 | GSE180098 | GEO

mRNA-seq of HCC1954 siControl and siRNF40

Project description:mRNA-seq of HCC1954 siControl and siRNF40

| PRJEB38971 | ENA

mRNA-seq of HCC1954 siControl and siUSP22

Project description:mRNA-seq of HCC1954 siControl and siUSP22

| PRJEB34048 | ENA

Expression data from lung SCC treated with DMSO and PXD101

Project description:We used microarrays to detail the global programme of gene expression in lung SCC cells treated with belinostat, a pan-HDAC inhibitor. The primary focus of this work is to investigate the efficacy of belinostat on lung SCC cells. Our phosphoproteomic profiling analyses revealed the downregulation of MAPK signaling pathway upon drug treatment, together with the induction of apoptosis. While HDAC inhibition generally affects transcription, the mechanism of SOS/MAPK downregulation was therefore proposed to be affected at the transcriptomic level. However, genes related to MAPK pathway were not significantly regulated upon belinostat treatment, whereas ubiquitin-proteasome gene signature was affected. This supports an indirect mechanism of epigenetic regulation on MAPK signaling that should be explored further.

2017-08-31 | GSE85979 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data