Rigidity of cell fate and function among monocytes (ATAC-Seq)

ABSTRACT: Here, we used an inducible and reversible system to pause myeloid differentiation at a self-renewing state. These cells were clonally isolated and allowed to differentiate to test whether function was clone-specific and clonally restricted. We found that monocytic subsets exist with inherent, restricted capabilities which differ in their capacity to perform traditional monocytic functions.

ORGANISM(S): Mus musculus

PROVIDER: GSE176048 | GEO | 2023/06/01

REPOSITORIES: GEO