RNA- and ATAC-seq data from hESCs differentiated with Wnt and Activin with or without CPI-203

ABSTRACT: We report genome-wide changes in chromatin state and transcriptional output following Wnt-priming and subsequent Activin induced differentiation of human embryonic stem cell and the effects of BET bromodomain inhibition during Wnt-priming. The two signals, Wnt and Activin, although provided sequentially, result in stable mesendoderm differentiation (Yoney et al., 2018).

ORGANISM(S): Homo sapiens

PROVIDER: GSE176222 | GEO | 2021/06/06

REPOSITORIES: GEO