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POWV isolate from Long Island infects brain endothelial cells and pericytes. [hBMECs]

ABSTRACT: POWV isolate from Long Island (POWV-LI-9) is released basolaterally from humban brain microvascular endothelial cells (hBMECs) and infects primary human brain vascular pericutes (hBVPs).

ORGANISM(S): Homo sapiens

PROVIDER: GSE176251 | GEO | 2021/06/08

REPOSITORIES: GEO

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POWV isolate from Long Island infects brain endothelial cells and pericytes. [hBVPs]

Project description:POWV isolate from Long Island (POWV-LI-9) is released basolaterally from humban brain microvascular endothelial cells (hBMECs) and infects primary human brain vascular pericutes (hBVPs).

2021-06-08 | GSE176252 | GEO

POWV isolate from Long Island infects brain endothelial cells and pericytes. [hBMECs]

Project description:POWV isolate from Long Island infects brain endothelial cells and pericytes. [hBMECs]

| PRJNA735635 | ENA

POWV isolate from Long Island infects brain endothelial cells and pericytes.

Project description:POWV isolate from Long Island infects brain endothelial cells and pericytes.

| PRJNA735632 | ENA

POWV isolate from Long Island infects brain endothelial cells and pericytes.

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-06-08 | GSE176253 | GEO

POWV isolate from Long Island infects brain endothelial cells and pericytes. [hBVPs]

Project description:POWV isolate from Long Island infects brain endothelial cells and pericytes. [hBVPs]

| PRJNA735636 | ENA

Impact of Neospora caninum infection on the transcriptome of cerebrovascular endothelial cells

Project description:We also used Affymetrix array technology to investigate the global alteration in the gene expression of human brain microvascular endothelial cells (hBMECs) and rat brain microvascular endothelial cells (rBMVECs) in response to N. caninum infection at 24 hours post infection.

2020-08-10 | E-MTAB-9411 | biostudies-arrayexpress

Cytotoxic and anti-Toxoplasma gondii activities of monensin on human brain microvascular endothelial cells

Project description:The aim of the present work was to investigate the effect of monensin on the in vitro growth of T. gondii tachyzoites and on the host cells (human brain microvascular endothelial cells - hBMECs). The hypotheses were that (1) inhibition of the WNT signalling pathway by monensin can reduce the growth of T. gondii infecting human brain microvascular endothelial cells (hBMECs) and (2) by suppression of the growth of T. gondii using monensin, impairment of the BBB integrity can be restored (3) inhibition of WNT pathway by monensin can be detected by microarray experiment.

2020-07-06 | E-MTAB-8817 | biostudies-arrayexpress

Zka virus (ZIKV) persistently infects primary human brain microvascular endothelial cells

Project description:ZIKV alters transcriptional responses of infected cells to avoid immune detection. We have compared the transcriptional responses of ZIKV-infected hBMECs and mock-infected hBMECs. Examination of transcriptional responses of ZIKV-infected hBMECs versus mock-infected hBMECs

2017-07-15 | GSE98889 | GEO

SUMO and SIM Sites Direct Nuclear Localization of the Zika Virus NS5 Protein and Regulate Endothelial Cell Transcriptional Responses

Project description:ZIKV NS5 WT expression in human brain microvascular endothelical cells (hBMECs) alters transcriptional responses and downregulate genes related to cell cycle, nucleosome formation and interferon stimulated genes (ISGs).

2020-04-02 | GSE147926 | GEO

Morphine-treated Primary Brain Endothelial Cells LC-MS/MS DIA

Project description:This project aimed at investigating the impact of morphine exposure on brain endothelial cells via an in vitro monoculture of primary human brain microvascular endothelial cells (HBMECs) and state of the art mass spectrometry-based proteomics, using a data-independent acquisition (DIA) MS-based quantitative approach. HBMECS were exposed to morphine at three different concentrations (1, 10, 100 uM) and for two different time points (24h and 48h) to explore dose- and time-dependent effects.

2022-03-21 | PXD024351 | Pride

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