Transcriptomics,Genomics

Dataset Information

55

Human peripheral blood cells: autoimmune diseases vs. healthy individuals


ABSTRACT: Gene expression profiling of peripheral blood cells from patients with rheumatoid arthritis (RA)/ systemic lupus erythematosus (SLE)/ polyarticular type juvenile idiopathic arthritis (polyJIA)/ systemic-onset JIA (sJIA) vs healthy children (HC) and healthy individual (HI). Overall design: Peripheral blood was obtained from patients with RA (n=112), SLE (n=22), polyJIA (n=6), sJIA (n=51), HC (n=8), and HI (n=45). Blood samples from 8 HC and 45 HI are used as control.

INSTRUMENT(S): Hitachisoft AceGene Human Oligo Chip 30K 1 Chip Version

SUBMITTER: Norihiro Nishimoto  

PROVIDER: GSE17755 | GEO | 2010-08-21

SECONDARY ACCESSION(S): PRJNA117863

REPOSITORIES: GEO

altmetric image

Publications

Underexpression of mitochondrial-DNA encoded ATP synthesis-related genes and DNA repair genes in systemic lupus erythematosus.

Lee Hooi-Ming HM   Sugino Hidehiko H   Aoki Chieko C   Nishimoto Norihiro N  

Arthritis research & therapy 20110415 2


INTRODUCTION: Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease characterized by various systemic symptoms and multiple organ damage. We clarify biological and functional abnormalities in SLE by comparing the gene expression profiles of SLE patients with those of healthy individuals. METHODS: Gene expression profiles from the peripheral blood of 21 SLE patients and 45 healthy individuals were obtained using a DNA microarray. Gene ontology analysis and network pathway analys  ...[more]

Similar Datasets

2010-10-01 | E-GEOD-20864 | ArrayExpress
2010-10-01 | GSE20864 | GEO
2019-02-18 | PXD011796 | Pride
2009-11-16 | E-GEOD-19033 | ArrayExpress
2015-05-14 | E-GEOD-45291 | ArrayExpress
2009-11-17 | GSE19033 | GEO
| GSE94815 | GEO
2007-11-01 | E-GEOD-7753 | ArrayExpress
2011-02-14 | GSE20307 | GEO
2011-02-14 | E-GEOD-20307 | ArrayExpress