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Gene expression profile of effector Treg cells isolated from spleens and tumors of tumor-bearing mice

ABSTRACT: A majority of effector Treg cells (eTregs) that are abundant in many types of tumors are marked by the expression of Blimp1. However, the specific impact of Blimp1+ eTregs on, and mechanisms of action within, tumors remain unknown. To better understand the role of Blimp1 in the regulation of eTreg function in the tumor immunity, we profiled the differential gene expression in Blimp1-deficient eTregs compared to WT control eTregs from tumor-bearing mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE178132 | GEO | 2021/11/24

REPOSITORIES: GEO

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