Global changes in granulosa cell transcription in response to the LH surge

ABSTRACT: During ovulation, the LH surge leads to the activation of various signalling cascades in granulosa cells, resulting in a critical shift in chromatin landscape and correspondingly the ovarian gene expression profile. Such large-scale genomic reprogramming involves a specific suite of ovulatory transcription factors. This study aims to characterise global changes in the chromatin landscape that are induced by the LH surge in granulosa cells during ovulation.

ORGANISM(S): Mus musculus

PROVIDER: GSE178314 | GEO | 2023/06/22

REPOSITORIES: GEO