Reconstructing aspects of human embryogenesis with pluripotent stem cells

ABSTRACT: We have established an in vitro model that reconstructs aspects of human embryogensis using human expanded potential pluripotent stem cells (hEPSCs). We performed single-cell RNA sequencing (scRNA-seq) on hEPSCs grown in 2D (prior to aggregation), hEP-structures at day 5, hEP-structures grown in IVC for 24h, and natural human blastocysts at day 5/6.

ORGANISM(S): Homo sapiens

PROVIDER: GSE178326 | GEO | 2021/08/13

REPOSITORIES: GEO