Whole transcriptome analysis of resveratrol and metformin improving high fat diet induced insulin resistance

ABSTRACT: Long non-coding RNAs (lncRNAs) play key roles in various diseases; however, their functions in insulin resistance are unclear. This study aimed to determine whether resveratrol or metformin could influence the expression of lncRNA and to elucidate the underlying mechanism. We conducted a high-throughput sequencing analysis to detect lncRNA and mRNA expression signatures of mice that were fed with HFD to induce IR.

ORGANISM(S): Mus musculus

PROVIDER: GSE178415 | GEO | 2021/06/18

REPOSITORIES: GEO