Genome-wide analysis of STAT6 target genes in IL-4 treated human cord blood CD4+ cells

ABSTRACT: STAT6 is a major transcription factor driving the polarization of Th2 cells in response to cytokine IL-4. Here we have analyzed on a genome wide level the STAT6 mediated gene expression after IL-4 induction in naive human CD4+ T cells. RNAi mediated STAT6 knockdown was used to reveal the genes specifically regulated by STAT6.

ORGANISM(S): Homo sapiens

PROVIDER: GSE17851 | GEO | 2010/06/25

SECONDARY ACCESSION(S): PRJNA123547

REPOSITORIES: GEO