Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome of Wdr5 and (or) p53 double knockout ESCs and embryoid bodies

ABSTRACT: This study describes the transcriptome profiling of day 6 SFEBq embryonic bodies (EBs): 1) WT; 2) Wdr5 KO ; 3) Wdr5 KO with T12h hWDR5 rescue; 4) Wdr5 KO with T48h hWDR5 rescue

ORGANISM(S): Mus musculus

PROVIDER: GSE178555 | GEO | 2021/06/22

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcriptome of day 6 EBs [WT, hWDR5iRescue,Wdr5 KO clone #3 with or without early (T12h) and late rescue (T48h)]

Project description:This study describes the transcriptome profiling of day 6 SFEBq embryonic bodies (EBs): 1) WT; 2) Wdr5 KO ; 3) Wdr5 KO with T12h hWDR5 rescue; 4) Wdr5 KO with T48h hWDR5 rescue

2019-11-21 | GSE116155 | GEO

Chromatin accessibility profiling of mouse embryonic stem cells and embryonic bodies using SFEBq differentiation methods upon Wdr5 and P53 deletion with or without WT or mutant hWDR5 rescue

Project description:This study describes time-course chromatin accessibility profiling of mouse ESC and embryonic bodies n Wdr5 and p53 knockout (with or without WT or mutant hWDR5 rescue)

2021-06-22 | GSE178551 | GEO

Genome profiling of WDR5, P53, H3K4Me3 binding in mouse embryonic bodies using SFEBq differetiation methods

Project description:This study describes the binding profile of WDR5, p53 and H3K4Me3 in mouse embryonic bodies at day 2 (WT, Wdr5 KO, Wdr5 and p53 double knockout)

2019-11-25 | GSE140899 | GEO

Genome profiling of HA-hWDR5 binding in mouse embryonic bodies using SFEBq differetiation methods

Project description:This study describes the binding profile of HA-hWDR5 in mouse embryonic bodies with early (T12h) and late (T48h) rescue of HA-hWDR5

2019-11-21 | GSE116154 | GEO

Transcriptome of Wdr5 and (or) p53 double knockout ESCs and embryoid bodies

Project description:Transcriptome of Wdr5 and (or) p53 double knockout ESCs and embryoid bodies

| PRJNA739656 | ENA

Chromatin accessibility profiling of mouse embryonic bodies using SFEBq differetiation methods upon transient mWdr5 deletion with or without hWDR5 rescue

Project description:This study describes time-course chromatin accessibility profiling of mouse embryonic bodies upon transient mWdr5 deletion with or without hWDR5 rescue

2019-11-21 | GSE116153 | GEO

Chromatin accessibility profiling of mouse embryonic stem cells and embryonic bodies using SFEBq differentiation methods upon Wdr5 and P53 deletion with or without WT or mutant hWDR5 rescue

Project description:Chromatin accessibility profiling of mouse embryonic stem cells and embryonic bodies using SFEBq differentiation methods upon Wdr5 and P53 deletion with or without WT or mutant hWDR5 rescue

| PRJNA739652 | ENA

Wdr5

Project description:Wdr5

| PRJNA739648 | ENA

Transcriptional Profiling of Hh-Treated Embryoid Bodies

Project description:This experiment was specifically designed to measure neural targets of Shh signaling, we sought to profile the genes upregulated by Hh signaling in the ventral neural tube to obtain a valid dataset. To obtain ventral-specific markers, we generated retinoic acid-treated EBs grown in the presence or absence of HH-Ag. We did not observe induction of ventral Hh markers in RA-treated constitutive Gli1FLAG EBs and used these for the control, baseline set. The presence of FoxA2, Nkx2.9 and Nkx6.1 amongst the top 10 genes based on expression levels suggests that profiling significantly enriches for Hh-dependent cell types. As expected, the benchmark standard Gli1 was not up-regulated in our array, since it is constitutively expressed in the control as well. Keywords: neural progenitors, embryoid bodies, differentiation, Hedgehog, retinoic acid

2007-04-20 | GSE4936 | GEO

Transcriptome of day 6 EBs [WT, hWDR5iRescue,Wdr5 KO clone #3 with or without early (T12h) and late rescue (T48h)]

Project description:Transcriptome of day 6 EBs [WT, hWDR5iRescue,Wdr5 KO clone #3 with or without early (T12h) and late rescue (T48h)]

| PRJNA477503 | ENA