Dataset Information


Titanium dioxide nanoparticles exposure

ABSTRACT: This project utilized oligonucleotide microarrays to examine gene expression patterns in adult male fathead minnows (Pimephales promelas) exposed to a common nanomaterial, titanium dioxide (TiO2, stearate-coated particles, MT-100TV®). We exposed adult male fathead minnows for 96 hr to three doses (0, 1, and 10 mg/L nominal) of TiO2 under static renewal conditions. TiO2 is stearate coated, 15 nm particle size. Overall design: Three-condition experiment: high dose, controls (untreated, low dose). Three tissues: liver, gill, brain. Biological replicates: 4 control replicates, 4 low dose, 4 high dose for gill and liver. One array for brain control and low dose; and 2 arrays for brain high dose. Contributor: Johnson & Johnson Worldwide Envrionmental

INSTRUMENT(S): EcoArray 1 x 22K Fathead Minnow Microarray (v1 and v2)

ORGANISM(S): Pimephales promelas  

SUBMITTER: Barbara Joan Carter   

PROVIDER: GSE17902 | GEO | 2010-12-22



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