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Transcriptome analysis of the effects of sorafenib and osimertinib in PC9 cells

ABSTRACT: The aim of the study was to characterize the gene expression profiles of PC9 cells exposed to sorafenib and osimertinib, alone or in combination. PC9 cells were cultured in presence of sorafenib and osimertinib for 1day, 2 days and 4 days. Genome-wide expression profiling (Agilent microarrays) were used to characterize the transcriptome of PC9 cells and to identify specific gene exptression signatures and functionally relevant gene networks linked to sorafenib and osimertinib treatments.

ORGANISM(S): Homo sapiens

PROVIDER: GSE179192 | GEO | 2025/05/26

REPOSITORIES: GEO

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