IRS1 phosphorylation determines a heritable probability of cancer cells to persist during EGFR inhibition therapy [Mars-seq]

ABSTRACT: As part of a multi-omic pursuit for mechanisms of persistency of cancer cells to drug treatment, we generated pair-wise transcriptome analysis of nearly 200 single-cell-derived clonal populations, with and w/o drug treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE179240 | GEO | 2021/07/05

REPOSITORIES: GEO