Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genes differentially methylated after DNA methyltransferase 1 (DNMT1) knockdown in the presence or absence of early osteoblast (OB) differentiation [RRBS]

ABSTRACT: reduced representation bisulfite sequencing (RRBS) sequencing was performed to analyze methylation profiles regulated by DNMT1 in C3H10T1/2 MSCs with or without OB differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE179903 | GEO | 2021/07/15

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Genes differentially expressed after DNA methyltransferase 1 (DNMT1) knockdown in the presence or absence of early osteoblast (OB) differentiation [RNA-seq]

Project description:RNA sequencing was performed to analyze potential genes regulated by DNMT1 in C3H10T1/2 MSCs with or without OB differentiation.

2021-07-15 | GSE179902 | GEO

Genes differentially expressed during early osteoblast (OB) differentiation

Project description:RNA-seq analysis was performed to identify early OB-regulating genes in C3H10T1/2 MSCs.

2021-03-20 | GSE169224 | GEO

Genes differentially methylated after DNA methyltransferase 1 (DNMT1) knockdown in the presence or absence of early osteoblast (OB) differentiation [RRBS]

Project description:Genes differentially methylated after DNA methyltransferase 1 (DNMT1) knockdown in the presence or absence of early osteoblast (OB) differentiation [RRBS]

| PRJNA745566 | ENA

RRBS (Reduced Representation Bisulfite Sequencing) of HL60

Project description:We exploited the methylation genome-scale screening RRBS to correlate the RNA species physically associated with DNMT1 and proximal to the annotated genes to the methylation status of the corresponding loci. Out of 15275 non ambiguous gene loci identified by DNMT1 RIP-Seq, 9436 loci were covered by RRBS. These 9436 loci were clustered according to the fold of specific DNMT1 library peaks enrichment (defined as the ratio of the sum of the area under the curve of specific DNMT1 library peaks covering the gene loci). Genes were then stratified by the expression profile ultimately leading to the epitranscriptome map, a comprehensive map cross-referencing DNMT1-interacting transcripts to (i) DNA methylation and (ii) gene expression profile. Relationship between DNMT1-RNA interactions, DNA methylation and gene expression

2012-12-01 | E-GEOD-32168 | biostudies-arrayexpress

Genes differentially expressed after DNA methyltransferase 1 (DNMT1) knockdown in the presence or absence of early osteoblast (OB) differentiation

Project description:Genes differentially expressed after DNA methyltransferase 1 (DNMT1) knockdown in the presence or absence of early osteoblast (OB) differentiation

| PRJNA745562 | ENA

A Dominant mutation in Dnmt1 leads epigenetic changes (rrbs)

Project description:A Dominant mutation in Dnmt1 leads epigenetic changes (rrbs)

| PRJNA715213 | ENA

Gene expression in the GWAT of ob/ob and ob/ob/Fsp27-/- mice

Project description:GWAT store most of the TAG in mice, ob/ob mice is an obese mice. Ob/ob/Fsp27-/- mice are lean when compared with ob/ob mice. The GWAT weight was dramatically reduced in ob/ob/Fsp27-/- mice. We next extract the total RNA from the GWAT of ob/ob and ob/ob/Fsp27-/- mice, to perform microaary analysis using Mouse Genome 430 2.0 arrays, Affymetrix. We then analysised the up-regulated and down regulated pathways.

2015-04-17 | GSE59807 | GEO

RRBS (Reduced Representation Bisulfite Sequencing) of HL60

2012-12-01 | GSE32168 | GEO

Gene expression in the GWAT of ob/ob and ob/ob/Fsp27-/- mice

2015-04-17 | E-GEOD-59807 | biostudies-arrayexpress

Gene Expression in the BAT and WAT of ob/ob and ob/ob/Cidea-/-/Cidec-/- mice

Project description:ob/ob mice is an obese mice. CIDE family proteins including Cidea, Cideb and Cidec play important role in lipid metabolism. Cidea is mainly expressed in the brown adipose tissue (BAT). Cidec is mainly expressed in the BAT and white adipose tissue (WAT). We generated ob/ob/Cidea-/-/Cidec-/- mice to investigate the phenotype of fat tissue. ob/ob/Cidea-/-/Cidec-/- mice are lean when compared with ob/ob mice. The tissue weight and TAG content of BAT and WAT was extreamly decreased in ob/ob/Cidea-/-/Cidec-/- mice compared with that in ob/ob mice. We next extract the total RNA from the BAT and WAT of ob/ob and ob/ob/Cidea-/-/Cidec-/- mice, to perform microarray analysis using Mouse Gene 1.0 ST array system, Affymetrix. We then analysised the up-regulated and down regulated pathways.

2018-04-18 | GSE100989 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data