10X Single cell RNAseq (scRNAseq) analysis of intestinal epithelial cells (IECs) from murine small intestinal organoids treated with vehicle (DMSO) or LXR agonist GW3965.

ABSTRACT: Intestinal organoids are a good model of in vitro tissue regeneration that faithfully recapitulates majority of cell types of the intestine. To analyze the impact of LXR activation in intestinal regeneration and overall cellular composition, organoids established from WT mice were treated with either vehicle (DMSO) or GW3965 and were analyzed using 10X scRNAseq platform.

ORGANISM(S): Mus musculus

PROVIDER: GSE180079 | GEO | 2024/07/19

REPOSITORIES: GEO