Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MRNA Expression Data from Murine Hearts of Wildtype Mice over 24 hours in normal light-dark environment (12:12)

ABSTRACT: Male C57Bl/6 mice were accommodated in normal 12:12 LD condition for one week. Hearts were collected every 4 hours over 24 h starting at 1 h before lights on (ZT23) (ZT23, ZT03, ZT07, ZT11, ZT15, ZT19). The microarray approach allows the investigation of daily transcriptome-wide gene expression changes in hearts over 24 hours.

ORGANISM(S): Mus musculus

PROVIDER: GSE180108 | GEO | 2021/07/16

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

mRNA Expression Data from Murine Hearts of Clock delta 19/delta 19 Mice over 24 hours in normal light-dark environment (12:12)

Project description:Male Clock delta 19/delta 19 mice were accommodated in normal 12:12 LD condition for one week. Hearts were collected every 4 hours over 24 h starting at 1 h before lights on (ZT23) (ZT23, ZT03, ZT07, ZT11, ZT15, ZT19). The microarray approach allows the investigation of daily transcriptome-wide gene expression changes in hearts over 24 hours.

2021-07-16 | GSE180109 | GEO

3' RNA-seq of flies over-expressing cabut protein or RNAi against cabut mRNA

Project description:CbtOE (Tim-gal4; UAS-cbtFLAG), Tim-gal4 (control for CbtOE), cbtRNAi (Tim-gal4-UAS-Dcr2-UAS-cbtIR-cbtE1) and Tim-gal4;UAS-Dcr2 (control for CbtRNAi) flies. Flies were entrained in LD (light: dark) condition for 3-4 days and harvested at six time points: ZT3, ZT7, ZT11, ZT15, ZT19, ZT23 Fly heads were collected, RNA was extracted and RNA-seq libraries were prepared as previously described (Engreitz et al., 2013) Three samples of cbtRNAi and three samples of their controls. Two samples of cbtOE with two samples of their controls.

2015-05-08 | E-GEOD-67590 | biostudies-arrayexpress

3' RNA-seq of flies over-expressing cabut protein or RNAi against cabut mRNA

2015-05-08 | GSE67590 | GEO

mRNA expression data from murine myocardial ischemia/reperfusion (mI/R) hearts following sleeptime or waketime captopril chronotherapy

Project description:Mice are 14 days post-mI/R (10 weeks old) on a C57Bl/6N background strain, hearts were collected at ZT15, following administration of saline placebo, sleeptime captopril (ZT01), or waketime captopril (ZT11) I.P. from day 7-14 post-mI/R. The microarray approach allows the investigation of gene expression changes of all genes in placebo vs. sleeptime vs. waketime vs. sham hearts.

2018-06-12 | GSE115568 | GEO

mRNA Expression Data from Murine Hearts of Transgenic Clock delta 19/delta 19 mice (Clock mice) and Wild type (WT) mice Fed a High-Fat (HFD) or Standard Chow (SC) Diet for 24 weeks

Project description:Mice are on a C57Bl/6J background strain, hearts were collected from Clock and WT mice at ZT07, following 24 weeks on either a HF or SC diet. The microarray approach allows the investigation of gene expression changes of all genes in Clock HFD vs. Clock SC vs. WT HFD vs. WT SC hearts.

2018-06-09 | GSE110245 | GEO

mRNA Expression Data from Murine Hearts of Wildtype Mice over 24 hours in normal light-dark environment (12:12)

Project description:mRNA Expression Data from Murine Hearts of Wildtype Mice over 24 hours in normal light-dark environment (12:12)

| PRJNA746577 | ENA

Microarray expression data from P50 mouse full thickness back skin of C57BL/6 mice - various durations of IMQ treatment and timepoints.

Project description:Imiquimod (IMQ) is a topical therapeutic immune activator that causes psoriasiform inflammation in mice. To determine if IMQ-induced inflammation and gene expression changes depended on the time of day in which treatment is administered, we performed gene expression profiling of dorsal mouse back skin by microarray after different durations of topical 1% IMQ treatment (control = no treatment, 6 hr, 24 hr, and 5 days of IMQ treatment) at different times of day (ZT01, ZT07, ZT09 = day-time treatment; ZT13 and ZT19 = night-time treatment). We also performed a time course after IMQ treatment by collecting mouse back skin after 0 (no treatment), 1, 2, 4, 6, and 24 hours post-treatment. Lastly, we determined gene expression changes in response to IMQ in mice deleted for the core circadian clock gene, Bmal1, after 0 (no treatment) and 24 hours post-1% IMQ compared to Wt (both treated and collected during the daytime at ZT09). The results of this study are important as they show that IMQ-induced activation of interferon sensitive genes are diurnal in Wt mice after 6 hours and 24 hours but not after 5 consecutive treatments. Furthermore, we find that interferon sensitive genes are induced more robustly in the skin of Bmal1 KO mice after 24 hr IMQ compared to Wt mice. These results are important for further understanding how the circadian clock regulates immune activation in response to the theraputic agent IMQ. In this dataset, we include the expression data obtained from 28 microarray samples, all of which were generated from whole back skin RNA samples pooled from 5-7 mice per sample.

2020-03-30 | GSE142165 | GEO

mRNA Expression Data from Murine Hearts of Clock delta 19/delta 19 Mice over 24 hours in normal light-dark environment (12:12)

Project description:mRNA Expression Data from Murine Hearts of Clock delta 19/delta 19 Mice over 24 hours in normal light-dark environment (12:12)

| PRJNA746578 | ENA

mRNA Expression Data from Murine Hearts of Wild type (WT) C57Bl/6 mice housed under a 12h light: 12h dark or 12h light: 4h blue: 8h dark cycle for 4 weeks

Project description:Mice are on a C57Bl/6N background strain, hearts were collected at ZT07, following 4 weeks under a 12h light: 12h dark (LD) or 12h light: 4h blue: 8h dark (LBD) cycle. The microarray approach allows the investigation of gene expression changes of all genes in WT LD vs. WT LBD hearts.

2018-06-12 | GSE115567 | GEO

Methylation data from CD4+ cells at birth and 12 months from a cohort of children who were diagnosed with IgE food allergy to either egg milk or peanut at 12 months (n=12) and healthy controls (n=12).

Project description:DNA methylation data derived from total CD4+ T-cells from a cohort of paediatric food allergy. There are 12 food allergic samples (6 activated and matched control), 12 non-allergic samples (6 activated and matched control) collected at birth and resample at 12-months, total 48 samples. Mononuclear cells were either activated with anti-CD3 (0.5 ug/mL) + IL2(20U) or rested in media alone for 24 hours. CD4+ cells were purified and DNA was harvested and bisulphite converted for methylation analysis on illumina HM450K array.

2011-12-22 | GSE34639 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data