Pulmonary epithelial and endothelial cell damage, loss of repair, inhibition of fibrinolysis and cellular senscence in fatal COVID-19

ABSTRACT: Key pulmonary findings included: 1) Loss or damage to respiratory epithelial basal cells, alveolar epithelial cells, 2) Impaired clot fibrinolysis with increased levels of plasma and lung PAI-1, and 3) modulation of cellular senescence markers.

ORGANISM(S): Homo sapiens

PROVIDER: GSE180226 | GEO | 2022/10/01

REPOSITORIES: GEO