Anti-CD4 treatment-induced IL18Rαhi CD8+ T cells show highly effector profile

ABSTRACT: Anti-CD4 monoclonal antibody, a prominent immunomodulatory agent, enriches IL18Rαhi CD8+ T cells that elicit robust anti-tumor immunity in B16F10 melanoma. To investigate gene-expression profile of IL18Rαhi subset, we conducted transcriptome analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE180439 | GEO | 2021/07/22

REPOSITORIES: GEO