Immune profiling in mice treated with BCL2 or JAK1/2 inhibitors

ABSTRACT: This study examined the impact of venetoclax or ruxolitinib on the immune profile of the bone marrow in treated mice showing venetoclax reduced expression of MHC-II and IFNg associated genes while ruxolitinib upregulated MHC-II and downregulated IFNg associated genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE181060 | GEO | 2021/10/13

REPOSITORIES: GEO