Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from human A549 cells and exosomes under room air (RA) or intermittent hypoxia (IH)

ABSTRACT: Studies have shown that IH may promote the development of non-small-cell lung cancer (NSCLC), Exosomes carry specific proteins, lipids, small molecule RNAs (miRNAs) as well as other bioactive substances, which play an important role in tumor growth. The role of exosomal miRNAs in the promotion of tumor development by IH has not been studied.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE181067 | GEO | 2021/07/29

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Expression data from human A549 cells and exosomes under room air (RA) or intermittent hypoxia (IH)

Project description:Expression data from human A549 cells and exosomes under room air (RA) or intermittent hypoxia (IH)

| PRJNA750503 | ENA

Time- and tissue-specific response of the mouse transcriptome after a short-term exposure to normoxia or intermittent hypoxia (IH)

Project description:To investigated the effects of early exposure to IH on tissue-specific transcriptome and biological processes, we evaluated differential gene expression of circadian rhythms and 24-hour mean expression in the lung, heart, liver, kidney, muscle, and cerebellum from mice after exposure to normoxic and IH conditions. The cardiopulmonary tissues were most affected by short-term exposure to IH in comparison with other organs.

2022-09-30 | GSE214530 | GEO

Expression data from adult Drosophila females [normoxia and IH]

Project description:High-fat diet (HFD) in normoxia causes a worsened phenotype in adult female flies compared to regular diet (RD). Intermittent hypoxia (IH) causes an opposite phenotype both when flies are on RD in IH compared to normoxia and even more dramatically when on HFD in IH compared to HFD in normoxia. We used microarrays to examine the transcriptional changes occurring both on a HFD compared to RD in normoxia, and when IH is introduced.

2015-05-30 | GSE47166 | GEO

microRNA expression in infantile hemangioma (IH) and normal skin tissues

Project description:To determine the microRNA expression profile in IH and non-tumor tissues, we uesed miRNA 4.0 microarray form Affymetrix to examine the expression of microRNA in IH and non-tumor tissues

2020-06-06 | GSE100682 | GEO

circRNA expression in infantile hemangioma (IH) and matched non-tumor tissues

Project description:To determine the circRNA expression profile in IH and matched non-tumor tissues, we uesed circRNA microArray analysis form Arraystar to examine the expression of circRNAs in IH and matched non-tumor tissues.

2019-05-09 | GSE98795 | GEO

Effects of intermittent and chronic hypoxia on HAEC

Project description:Intermittent hypoxia (IH) in HeLa cell culture activates proinflammatory transcription factor NFκB, whereas chronic hypoxia (CH) does not. In order to determine whether IH may be linked to vascular inflammation, we developed a novel IH cell culture system and exposed HAEC (human aortic endothelial cells) to IH or CH. Keywords: Human Artery Endothelial Cells (HAEC)

2008-12-31 | GSE10723 | GEO

GNPS_2017 Mouse intermittent hypoxia (IH) - Blood plasma

Project description:2017 Mouse intermittent hypoxia (IH) - Blood plasma Contains LC/MS data for 10-week experiments involving mice raised in environments with normal oxygen, intermittent hypoxia (IH).

2019-02-25 | MSV000083481 | GNPS

GNPS_2018 Mouse intermittent hypoxia (IH) - Blood plasma

Project description:2018 Mouse intermittent hypoxia (IH) - Blood plasma Contains LC/MS data for 10-week experiments involving mice raised in environments with normal oxygen, intermittent hypoxia (IH) and intermittent hypercapnia (IC)

2019-02-25 | MSV000083482 | GNPS

Chronic Intermittent Hypoxia Increases Alveolar Surface Area in Adult Mice

Project description:Obstructive sleep apnea (OSA) leads to increased cardiovascular morbidity and mortality, which have been attributed to intermittent hypoxia (IH). The effects of IH on lung structure and function are unknown. We used a mouse model of chronic IH, which mimics the O2 profile in patients with OSA. We exposed adult C57BL/6J mice to 3 months of IH with an FIO2 nadir of 5%, 60 times/hr during the 12hr light phase. Control mice were exposed to room air. Gene microarrays were performed in a separate subset of animals (IH, n = 5; control, n = 5). Total RNA was isolated from lung tissue using the Trizol Reagent method, gene microarrays were performed with the Affymetrix GeneChipÂ® Mouse Genome 430A 2.0 Array (MG 430A 2.0; Affymetrix, Inc., Santa Clara, CA) and analyzed using Significance Analysis of Microarray (SAM) software.

2010-12-31 | E-GEOD-21409 | biostudies-arrayexpress

GNPS_2017 Mouse intermittent hypoxia (IH) - Aorta & pulmonary artery

Project description:2017 Mouse intermittent hypoxia (IH) - Aorta & pulmonary artery Contains LC/MS data for 10-week experiments involving mice raised in environments with normal oxygen, intermittent hypoxia (IH).

2019-02-25 | MSV000083483 | GNPS

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data