Transcriptomic changes following CENP-E partial depletion in normal human fibroblasts

ABSTRACT: Being CENP-E function restricted to mitosis, its haploinsufficiency has been used to study the induced cell aneuploidy. However, the gene expression profile triggered by CENP-E reduction in normal cells has never been explored. To fill this gap, here we investigated whether a gene network associated with siRNAs-induced CENP-E 50% reduction and consequent aneuploidy exists

ORGANISM(S): Homo sapiens

PROVIDER: GSE181191 | GEO | 2021/10/06

REPOSITORIES: GEO