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Spatial charting of single-cell transcriptomes in tissues

ABSTRACT: We performed single-cell RNA sequencing and spatial transcriptomics experiments on two ductal carcinoma in situ tissues and applied CellTrek to identify tumor subclones that were restricted to different ducts, and specific T cell states adjacent to the tumor areas. Our data show that CellTrek can accurately map single cells in diverse tissue types to resolve their spatial organization.

ORGANISM(S): Homo sapiens

PROVIDER: GSE181254 | GEO | 2022/02/25

REPOSITORIES: GEO

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