The role of Hippo pathway in ER positive breast cancer

ABSTRACT: We report the transcriptional difference of LATS1/2 gene knock out T47D cells with wild type control using RNA-seq technology. We further generated the chromatin binding of multiple proteins, including YAP, TEAD2, Estrogen receptor alpha, VGLL3 and several histone marks, as well as ATAC profiling between LATS1/2 gene knock out MCF7 cells with wild type control.

ORGANISM(S): Homo sapiens

PROVIDER: GSE181460 | GEO | 2022/01/11

REPOSITORIES: GEO