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Microbiota orchestrates monocyte reprogramming of the tumor microenvironment via type I IFN-STING axis to promote anticancer immunity

ABSTRACT: This study sets out to investigate the mechanisms by which gut microbiota controls the mononuclear phagocyte compartment of the tumor microenvironment to elicit effective anti-tumor responses. This dataset contains single-cell RNA sequencing data of leukocytes from murine subcutaneous EL4 lymphomas from mice with intact or absent microbiota.

ORGANISM(S): Mus musculus

PROVIDER: GSE181745 | GEO | 2021/10/09

REPOSITORIES: GEO

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