Genomics

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A chromatin immunoprecipitation database for prokarytic organisms [NAP]


ABSTRACT: Bacterial transcription factors (TFs) regulate gene expression to adapt to changing environments; when combined, the TF’s regulatory actions comprise transcriptional regulatory networks (TRNs). The chromatin immunoprecipitation (ChIP) assay is the major contemporary method for mapping in vivo protein-DNA interactions in the genome. It enables the genome-wide study of transcription factor binding sites (TFBSs) and gene regulation. Although rapidly accumulating publicly-available ChIP data are a valuable resource for the study of gene regulation, there are no full datasets of key regulators and nucleoid associated proteins (NAPs) in E. coli K-12 MG1655. Here, we present the genome-wide binding for dozens of major TFs and NAPs in the E. coli K-12 MG1655.

ORGANISM(S): Escherichia coli K-12

PROVIDER: GSE181767 | GEO | 2021/08/15

REPOSITORIES: GEO

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