RNASeq analysis of in vitro generated myeloid-derived supressor cells (MDSCs)

ABSTRACT: Several mechanisms have been implicated in MDSC-mediated suppression of immune responses. To better understand the mechanism(s)/pathway(s) MDSCs utilize to suppress immune responses, we performed a transcriptome profiling of CD11b+CD11c+ (good suppressors) and CD11b+CD11c- (poor suppressors) MDSCs. Comparison of the respective transcriptomes allowed us to identify target genes associated with immunosuppression.

ORGANISM(S): Mus musculus

PROVIDER: GSE182262 | GEO | 2021/10/05

REPOSITORIES: GEO