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Oligodendrocyte regulation during autoimmune neuroinflammation

ABSTRACT: The present study had the purpose to analyze the transcriptional state of oligodendrocytes in an animal model of multiple scleroris resembling autoimmune neuroinflammation and compared with control mice treated with ovalbumin. The results revealed that oligodendrocytes from the EAE (experimental autoimmune encephalomyelitis) model upregulate genes that are involved in immune processes providing evidence that oligodendrocytes can develop an immune phenotype in particular neuroinflammatory conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE182341 | GEO | 2021/08/21

REPOSITORIES: GEO

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