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Penetrating ballistic brain injury produces acute alterations in sleep and circadian-related genes in the rodent cortex: A preliminary study

ABSTRACT: We performed transcriptional profiling in an established rodent model of penetrating ballistic brain injury (PBBI) in conjunction with continuous sleep pattern recording of the first 24 hours after injury. 12 adult male Sprague-Daley rats that were randomized to PBBI (n=6) or sham (n=6) groups, animals received a right unilateral frontal PBBI, then were sacrificed after 24 hours of EGG/EMG recording. Brains were harvested, underwent sectioning and cortical tissue samples were stored. RNA were isolated from tissue samples.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE182360 | GEO | 2021/09/30

REPOSITORIES: GEO

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