Metabolic control of histone demethylation

ABSTRACT: To analyze whether metabolites regulate histone methylation in plants, we examined genome-wide histone 3 lysine-27 trimethylation (H3K27me3) in an Arabidopsis dehydrogenase mutant (ogdh1/2) by ChIP-seq. We found that the levels of H3K27me3 were reduced at various loci in ogdh1/2 relative to wild type, indicating that metabolites control histone demethylation in Arabidopsis.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE182411 | GEO | 2023/07/14

REPOSITORIES: GEO