Methylation profiling

Dataset Information

0

DNA methylation of a novel regulatory element within the tyrosine hydroxylase gene (TH) is dysregulated by chronic cocaine dependence in the human striatum

ABSTRACT: This study investigates differences in DNA methylation that are associated with chronic cociane dependence in post-mortem nucleus accumbens tissue samples from human brain. The data were generated with reduced representation bisulfite sequencing (RRBS) and compared to data generated in accumbens tissue from psychiatrically healthy controls.

ORGANISM(S): Homo sapiens

PROVIDER: GSE182585 | GEO | 2021/08/25

REPOSITORIES: GEO

Json Xml

Similar Datasets

Genomics DNA methylation of a novel regulatory element within the tyrosine hydroxylase gene (TH) is dysregulated by chronic cocaine dependence in the human striatum
| PRJNA756973 | ENA
Unknown Genetic diversity of tyrosine hydroxylase (TH) and dopamine ?-hydroxylase (DBH) genes in cattle breeds.
| S-EPMC3389531 | biostudies-literature
Unknown Pharmacogenetics of Dopamine ?-Hydroxylase in cocaine dependence therapy with doxazosin.
| S-EPMC6119656 | biostudies-literature
Genomics circRNAs in the mouse nucleus accumbens (ventral striatum) after cocaine conditioned place preference (CPP)
2020-06-27 | GSE153377 | GEO
Methylation profiling Cocaine-related DNA methylation in neurons in the caudate nucleus alters the three dimensional structure of the IRXA gene cluster
2021-09-11 | GSE137364 | GEO
Unknown Identification of Toxoplasma Gondii Tyrosine Hydroxylase (TH) Activity and Molecular Immunoprotection against Toxoplasmosis.
| S-EPMC7349186 | biostudies-literature
Unknown Tyrosine hydroxylase deficiency-Clinical insights and a novel deletion in TH gene in an Indian patient.
| S-EPMC7203656 | biostudies-literature
Transcriptomics Cocaine-regulated expression of striatal microRNAs
2011-05-13 | E-GEOD-29261 | biostudies-arrayexpress
Unknown NAD+ cellular redox and SIRT1 regulate the diurnal rhythms of tyrosine hydroxylase and conditioned cocaine reward.
| S-EPMC6215755 | biostudies-literature
Unknown Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3?.
| S-EPMC4125734 | biostudies-literature