ATAC-seq of MORC3 deficient BLaER1 monocytes [ATAC-seq]

ABSTRACT: We have identified MORC3 as a negative regulator of Type I Interferon (IFN), whose absence induces IFN and interferon-stimulated genes (ISGs). To study the global effects of MORC3 on DNA accessibility, we deleted MORC3 in IFNAR1-/- IFNAR2-/- BLaER1 monocytes and performed ATAC-seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE182752 | GEO | 2021/11/01

REPOSITORIES: GEO