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EQTL mapping of fetal-like pancreatic progenitor cells

ABSTRACT: The goal of this study is to understand the effects of genetic variation on gene expression in fetal-like pancreatic progenitor cells. We generated bulk RNA-seq from 107 iPSC-derived pancreatic progenitor cells (iPSC-PPC) from iPSC lines derived from 106 individuals from the iPSCORE resource. We then conducted genome-wide expression quantitative trait loci analyses to identify genetic variants associated with gene expression and isoform usage.

ORGANISM(S): Homo sapiens

PROVIDER: GSE182758 | GEO | 2023/10/03

REPOSITORIES: GEO

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Functional genomic analyses of iPSC-derived pancreatic progenitor cells

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WNT7 Promotes Proliferation of Pancreatic Progenitor Cells Differentiated from Human Pluripotent Stem Cells through Non-Canonical Wnt Signaling Pathway

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