Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

ABSTRACT: We report the effect of H19 knockdown on genome wide methylation by Enhanced Reduced Representation Bisulfite Sequencing (eRBBS) to detect quantitative base pair changes. Differential methylation genome wide analysis was done on NEPC derived organoid expressing shH19 or a control vector.

ORGANISM(S): Homo sapiens

PROVIDER: GSE182914 | GEO | 2021/09/12

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer [ChIP-seq]

Project description:To determine the functional epigenetic landscape of changes induced by H19, ChIP-seq was performed on H3K27me3 and H3K4me3 in V16D CRPC cells transduced with H19 (to induce NEtD) versus V16D CRPC control cells. Comaparison of genome-wide maps of chromatin state in V16D CRPC cells with and without H19 overexpression.

2021-09-15 | GSE183983 | GEO

Genome-wide DNA methylation change due to lncRNA H19 knockdown in myotubes

Project description:We used Methyl-MiniSeq platform from Zymo Research company to identify genome-wide methylation changes affected by lncRNA H19 knockdown in myotubes. Following H19 knockdown, we observed extensive genome-wide mthylation pattern changes relative to siCon cells, with some genes showing incresed methylation, others showing decreased methylation, and a third group with no significant change. Myotubes differentiated from mouse C3H myoblasts were transfected with either control siRNA or siH19, 48h later, cellular genomic DNA was extracted and subjected to genome-scale DNA methylation mapping using the platform of an improved version of Reduced Representation Bisulfite Sequencing (RRBS).

2015-11-09 | E-GEOD-73013 | biostudies-arrayexpress

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer.

Project description: Not available

| S-EPMC8692330 | biostudies-literature

Genome-wide DNA methylation change due to lncRNA H19 knockdown in myotubes

2015-11-09 | GSE73013 | GEO

Genome-wide DNA methylation change due to H19 knockdown and TET3 knockdown in UtLM

Project description:We used Methyl-MiniSeq platform from Zymo Research company to identify genome-wide methylation changes affected by H19 knockdown and TET3 knockdown in human UtLM. Following H19 and TET3 knockdown, we observed extensive genome-wide methylation pattern changes relative to siCon cells, with some genes showing increased methylation, others showing decreased methylation, and a third group with no significant change.

2021-07-16 | GSE117190 | GEO

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

Project description:The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

| PRJNA758288 | ENA

Identification of genes regulated by Long noncoding RNA H19 in hepatic cells

Project description:We used high throughput sequencing to compare the differential gene expression of HepG2 cells with and without H19 knockdown. We found critical genes involved in glucose production changed significantly after H19 konckdown compared to control.

2018-08-30 | GSE103201 | GEO

Identification of genes regulated by long noncoding RNA H19 in skeletal muscle

Project description:Soleus muscle has the most abundant H19 expression compared to other skeletal muscle tissues. In order to identify genes regulated by long noncoding RNA H19 in skeletal muscle, we performed RNA-Seq with dissected WT and H19KO soleus muscles from 21 week old mice. Among the differentially expressed genes, we found skeletal muscle - overexpressed gene DUSP27, which potentially plays an important role in regulating skeletal muscle glucose metabolisim by regulating the activitiy of AMPK, might be a target of H19 mediated regulation.

2018-08-30 | GSE103202 | GEO

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer [ChIP-seq]

Project description:The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer [ChIP-seq]

| PRJNA762568 | ENA

Identification of genes regulated by long noncoding RNA H19 in the ovary.

Project description:In order to identify genes regulated by long noncoding RNA H19 in the ovary, we performed RNA-Seq with WT and H19KO ovaries from 8-week old mice. Among the differentially expressed genes, we found anti-mullerian hormone (AMH), which potentially plays an important role in regulating ovarian follicular development, might be a target of H19 mediated regulation.

2019-05-08 | GSE114182 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data