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Transcriptome of chicken spleens with Escherichia coli infection

ABSTRACT: Purpose: the goals of this study was to find the differential genes of spleen in chickens infected with Escherichia coli Methods: The spleen samples from control group and the spleen samples from infection group were generated by deep sequencing using Illumina system with 9 biological repetitions and 2 technical repetitions, respectively. Results: Using an optimized data analysis workflow, we mapped about 68-91 million sequence reads per sample to the chicken spleens from the infection and control group by Hisat2. Approximately a quarter of the transcripts showed differential expression between the infection and control group, with a 5x SD fold change and p value <0.05.

ORGANISM(S): Gallus gallus

PROVIDER: GSE182967 | GEO | 2023/01/11

REPOSITORIES: GEO

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