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Adrenal gland gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice

ABSTRACT: The objective of the experiment is to determine the genes differentially expressed in the adrenal gland of the chromogranin A knockout mouse (Mahapatra et al., 2005).

ORGANISM(S): Mus musculus

PROVIDER: GSE18304 | GEO | 2010/03/03

SECONDARY ACCESSION(S): PRJNA123317

REPOSITORIES: GEO

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Adrenal gland gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice

Project description:The objective of the experiment is to determine the genes differentially expressed in the adrenal gland of the chromogranin A knockout mouse (Mahapatra et al., 2005). Adrenal glands from chromogranin A knockout mice (n=3) and wild-type control mice (n=3).

2010-03-15 | E-GEOD-18304 | biostudies-arrayexpress

Liver gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice

Project description:The objective of the experiment is to determine the genes differentially expressed in the liver of the chromogranin A knockout mouse (Mahapatra et al., 2005).

2010-03-03 | GSE18305 | GEO

Liver gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice

Project description:The objective of the experiment is to determine the genes differentially expressed in the liver of the chromogranin A knockout mouse (Mahapatra et al., 2005). Liver from chromogranin A knockout mice (n=3) and wild-type control mice (n=3).

2010-03-16 | E-GEOD-18305 | biostudies-arrayexpress

Gene expression from chromogranin A knockout mice vs. wild-type mice

Project description:This SuperSeries is composed of the following subset Series: GSE18304: Adrenal gland gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice GSE18305: Liver gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice Refer to individual Series

2010-03-03 | E-GEOD-18332 | biostudies-arrayexpress

Transcription profiling of mouse adrenal gland from Wildtype and Per2Cry1 double mutant mice - time series

Project description:This SuperSeries is composed of the following subset Series:; GSE4238: rhythmic transcriptome in the murine wt adrenal; GSE4239: Transcriptome regulation in the adrenal gland of circadian clock deficient Per2Cry1 double mutant mice Experiment Overall Design: Refer to individual Series

2008-06-20 | E-GEOD-4253 | biostudies-arrayexpress

WGBS from adrenal gland (ENCSR741FVM)

Project description:WGBS sequencing from adrenal gland tissue For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2019-03-03 | GSE127311 | GEO

WGBS from adrenal gland (ENCSR042LOG)

2019-03-03 | GSE127282 | GEO

eCLIP from adrenal gland (ENCSR096YAP)

Project description:eCLIP control experiment on adrenal gland against HNRNPU For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2017-01-03 | GSE91477 | GEO

eCLIP from adrenal gland (ENCSR634MFO)

Project description:eCLIP experiment on adrenal gland from the GTEx collection against DGCR8 For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2021-06-15 | GSE177629 | GEO

Unravelling the sex-specific diversity and functions of adrenal gland macrophages (RNA-Seq).

Project description:Despite the ubiquitous function of macrophages across the body, the diversity, origin, and function of adrenal gland macrophages remain largely unknown. We defined the heterogeneity of adrenal gland immune cells using single-cell RNA sequencing and used genetic models to explore the developmental mechanisms yielding to macrophage diversity. We defined populations of monocyte-derived and embryonically seeded adrenal gland macrophages and identified a female-specific subset with low MHC-II expression. In adulthood, monocyte recruitment dominated adrenal gland macrophage maintenance in female mice, while self-proliferation was more important in males. Adrenal gland macrophage sub-tissular distribution followed a sex-dimorphic pattern, with MHC-IIlow macrophages located at the border between the cortex and the medulla. Macrophage sex dimorphism depended on the presence of the cortical Xzone. Forcing X-zone maintenance in males, or its degradation in females, directly impacted the presence of MHC-IIlow macrophages. Adrenal gland macrophage depletion resulted in altered tissue homeostasis, modulated lipid- metabolism and decreased local aldosterone production during stress exposure. Overall, these data explain the heterogeneity of adrenal gland macrophages and point toward sexrestricted distribution and functions of these cells.

2022-05-23 | GSE203096 | GEO

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