Tet2 deficiency altered hematopoietic stem and progenitor cells ageing process

ABSTRACT: we compared self-renewal and lineage specification of WT and Tet2-deficient HSPCs during ageing and demonstrated that Tet2 ablation alters age-dependent HSC functional decline, revealing a disparate ageing process in the Tet2-deficient haemopoietic system.

ORGANISM(S): Mus musculus

PROVIDER: GSE183675 | GEO | 2023/08/11

REPOSITORIES: GEO