Lin28A/CENPE promoting the proliferation and chemo-resistance of acute myeloid leukemia

ABSTRACT: Peripheral blood samples of 3 refractory/relapsed AML patients (R/R-AML, relapsed/refractory AML patients who failed to achieve complete remission/CR after 2 courses of induction chemotherapy), 3 refractory secondary AML patients (S-AML, MDS or MPN derived AML patients did not reach CR after 2 rounds of induction chemotherapy), 4 de novo AML patients (AML, CR after standard “3+7” induction chemotherapy), and 3 healthy controls (HC) were collected. Nanodrop was applied to quantify the total RNA samples. Illumina kits were used to prepare the RNA-seq library.

ORGANISM(S): Homo sapiens

PROVIDER: GSE183817 | GEO | 2021/09/10

REPOSITORIES: GEO