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RNA sequencing of preB-ALL NALM-6 cells with or without XIAP-knockdown, using prime-seq

ABSTRACT: In this study we performed molecular manipulation of XIAP in vivo using microRNA-30 flanked shRNA expression in cell lines models of r/r ALL. Interestingly, upon strong XIAP knockdown, r/r ALL cells were outcompeted in vivo, while intermediate knockdown sensitized cells to chemotherapy. Using prime-seq we wanted to characterized NALM-6 cells expressing different XIAP levels.

ORGANISM(S): Homo sapiens

PROVIDER: GSE184011 | GEO | 2021/09/15

REPOSITORIES: GEO

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RNA sequencing of preB-ALL NALM-6 cells with or without XIAP-knockdown, using prime-seq

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