Genomics

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MicroRNA-592 inhibits the progression of breast cancer through targeting CYP20A1


ABSTRACT: Previous studies have shown that miR-592 may play an important role in the development of various cancer types. However, the mechanism of miR-592 in breast cancer progression remains unclear. Functional analysis showed that overexpression of miR-592 significantly inhibited the cell proliferation, clonal formation, and migration and invasion of MCF-7 cells in vitro. RNA sequencing (RNA-seq) was then used to identify the significantly dysregulated genes and enriched pathways in response to miR-592 overexpression in MCF-7 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE184253 | GEO | 2022/12/22

REPOSITORIES: GEO

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